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Friday, February 19, 2021

Zahorsky's syndrome I

An acute viral disease on infants and young children, characterized by prodromal high fever which disappears after 2 to 5 days and is followed by morbilliform rash. Recovery is complete. It is caused by human herpes virus 6. It was originally called the Sixth Disease to differentiate it from other exanthemas.

Zahorsky's syndrome I
 Zahorsky's syndrome I

The virus is transmitted though respiratory secretions. So when a child who has roseola sneezes, talks, or coughs, tiny droplets are sent into the air, allowing others to breathe in the virus. The virus droplets can also land on surfaces and another child can touch that surface and then put their hands in their mouth or nose and become infected.

The infection can be confused with the flu since symptoms are very similar (fever, runny nose, sore throat, cough). However, towards the end of infection, the child will usually develop a pink-colored rash. (Not all children develop this rash). The rash begins on the torso and then spreads to the arms, legs, neck and face. The pink spots can be flat or raised, and some may have a halo or lighter ring around them. Symptoms of the infections normally last 5 to 15 days. 

More details: 📖 Succinct Pediatrics: Evaluation and Management for Infectious Diseases and Dermatologic Disorders 

John Zahorsky (1871 - 1963), American paediatrician.

John Zahorsky
John Zahorsky



John Zahorsky was the son of John Zahorsky and Amalia Zahorsky, née Gura, Hungarian immigrants who moved to Steelville, Missouri, when he was seven year old. The name Zahorsky has been traced to the Polish word, Zagorza, which signifies "from the hills." Zahorsky means, therefore, the family from the hills.
To pay for his way through Missouri Medical College (since absorbed by Washington University), he worked as a pharmacist, file clerk and ladies' wear salesman.
On June 27, 1900, John Zahorsky married Carrie Elizabeth Silverwood (1876-1947) in St. Louis, Missouri. They had a daughter and a son.
John Zahorsky was Professor of Pediatrics and Director of the Department of Pediatries, St. Louis University School of Medicine, St. Louis. After more than 40 years as a specialist in paediatrics and practicing in big St. Louis hospitals, Zahorsky went back to his old home town, Steelville, Missouri, to practice as a country doctor.
He was buried in Steelville Cemetery, Crawford County, Missouri.

References

1: Mullins TB, Krishnamurthy K. Roseola Infantum. 2020 Jul 10. In: StatPearls
[Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan–. PMID:
28846307.

2: MONNET P. [Sixth disease]. Clinique (Paris). 1962 Mar;57:137-46. French.
PMID: 13936061.

3: Stone RC, Micali GA, Schwartz RA. Roseola infantum and its causal human
herpesviruses. Int J Dermatol. 2014 Apr;53(4):397-403. doi: 10.1111/ijd.12310.
PMID: 24673253.

4: Prober C. Sixth disease and the ubiquity of human herpesviruses. N Engl J
Med. 2005 Feb 24;352(8):753-5. doi: 10.1056/NEJMp048302. PMID: 15728806.

5: Janovský P. Sestá nemoc--exantema subitum [Sixth disease--exanthema subitum].
Cesk Pediatr. 1992 Sep;47(9):551-2. Czech. PMID: 1394570.

6: Hubácek P, Hrdlicková A, Zajac M. Chromozomální integrace sestého lidského
herpesviru (HHV-6) [Chromosomal integration of the sixth human herpes virus
(HHV-6)]. Epidemiol Mikrobiol Imunol. 2012 Sep;61(3):58-66. Czech. PMID:
23173298.

7: Raoof N, Batty R, Carroll TA, Pepper IM, Sandison A, Eckersley R, Hickman SJ.
Relapsing-Remitting Sixth Nerve Palsy in Association with Ollier's Disease.
Neuroophthalmology. 2015 Feb 3;39(2):92-95. doi: 10.3109/01658107.2014.998772.
PMID: 27928339; PMCID: PMC5123044.

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